Fold change and p-value cutoffs significantly alter microarray interpretations
نویسندگان
چکیده
منابع مشابه
A comparison of fold-change and the t-statistic for microarray data analysis
It has recently been suggested that differentially-expressed genes in a microarray experiment are best identified using fold-change, rather than a t-statistic, because the former results in lists of differentially-expressed genes that are more reproducible (Shi et al. 2005, Guo et al. 2006, MAQC Consortium 2006). We argue that reproducibility does not imply accuracy, and we show that the questi...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2012
ISSN: 1471-2105
DOI: 10.1186/1471-2105-13-s2-s11